Human spirituality is at a crossroads. Spiritual care providers and clergy encounter this reality on a daily basis. The “old” ways of framing experiences and crises are becoming less effective for an increasing number of people, regardless of their religious traditions. Fear and insecurity permeate our culture to such an extent that many people have become stuck within spiritual frameworks that are no longer as helpful or healthy as they may have been generations ago. A new framework, or perhaps new interpretations of the human spiritual experience, are needed. I propose that pneumaplasticity, the ability of human spirituality to rewire itself, is a key factor in making these necessary changes. As human beings learn to cultivate our pneumaplasticity, we will begin to also rewire our fear, and to embrace our full potential. We will begin to affirm our common humanity, to discover new ways of forming community, and to articulate new and renewed senses of meaning and purpose.